Epitope specificity of antibodies raised against enterotoxigenic Escherichia coli CFA/I fimbriae in mice immunized with naked DNA.

@article{Alves1998EpitopeSO,
  title={Epitope specificity of antibodies raised against enterotoxigenic Escherichia coli CFA/I fimbriae in mice immunized with naked DNA.},
  author={Adriana Maria Alves and Marcio O. Lasaro and Darcy F. de Almeida and Lu{\'i}s Carlos Santos Ferreira},
  journal={Vaccine},
  year={1998},
  volume={16 1},
  pages={
          9-15
        }
}
The cfaB gene, coding for the CFA/I fimbrial adhesin of enterotoxigenic Escherichia coli (ETEC), was cloned and expressed as a fusion peptide with the glycoprotein D (gD) from herpes simplex virus type 1 (HSV) in the pRE4 eukaryotic expression vector, resulting in the recombinant plasmid pRECFA. All BALB/c mice injected intramuscularly (i.m.) with a single dose (100 micrograms) of the purified plasmid developed antibodies against epitopes found on dissociated CFA/I subunits as well as other… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-4 OF 4 CITATIONS

New vaccine strategies against enterotoxigenic Escherichia coli. I: DNA vaccines against the CFA/I fimbrial adhesin.

  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 1999
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED