Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin.

@article{Lee1999EpitopeMO,
  title={Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin.},
  author={S J Lee and Mary C. Gray and Lihe Guo and Peter {\vS}ebo and Erik L. Hewlett},
  journal={Infection and immunity},
  year={1999},
  volume={67 5},
  pages={2090-5}
}
Adenylate cyclase (AC) toxin from Bordetella pertussis is a 177-kDa repeats-in-toxin (RTX) family protein that consists of four principal domains; the catalytic domain, the hydrophobic domain, the glycine/aspartate-rich repeat domain, and the secretion signal domain. Epitope mapping of 12 monoclonal antibodies (MAbs) directed against AC toxin was conducted… CONTINUE READING