Epitope mapping and features of the epitope for monoclonal antibodies inhibiting enzymatic activity of Helicobacter pylori urease.

@article{Fujii2004EpitopeMA,
  title={Epitope mapping and features of the epitope for monoclonal antibodies inhibiting enzymatic activity of Helicobacter pylori urease.},
  author={Ryoji Fujii and Fumiko Morihara and Takashi Oku and Emi Hifumi and Taizo Uda},
  journal={Biotechnology and bioengineering},
  year={2004},
  volume={86 4},
  pages={434-44}
}
Two characteristic monoclonal antibodies (HpU-2 and -18) out of 26 monoclonal antibodies (HpU-1 approximately 26) produced against Helicobacter pylori (H. pylori) urease showed a strong inhibitory effect against the enzymatic activity of the urease. Epitope mapping about some monoclonal antibodies of the HpU-series inhibiting enzymatic activity was performed by using a surface plasmon resonance apparatus and by digesting H. pylori urease with trypsin, followed by mass spectroscopy. The… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Immunological features and efficacy of a multi-epitope vaccine CTB-UE against H. pylori in BALB/c mice model

Applied Microbiology and Biotechnology • 2013
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…