Epithelioid sarcoma expresses epidermal growth factor receptor but gene amplification and kinase domain mutations are rare

@article{Cascio2010EpithelioidSE,
  title={Epithelioid sarcoma expresses epidermal growth factor receptor but gene amplification and kinase domain mutations are rare},
  author={Michael J Cascio and Richard J O'Donnell and Andrew E Horvai},
  journal={Modern Pathology},
  year={2010},
  volume={23},
  pages={574-580}
}
Epithelioid sarcoma is a rare, malignant, soft tissue neoplasm that can be classified into proximal, distal and fibroma-like subtypes. Regardless of subtype, epithelioid sarcoma often shows morphologic and immunophenotypic evidence of epithelial differentiation. Current therapeutic strategies include surgical resection, amputation, radiation or chemotherapy, although the overall prognosis remains poor. The epidermal growth factor receptor (EGFR) is a novel therapeutic target in carcinomas. In… CONTINUE READING
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Enzinger and Weiss’s Soft Tissue Tumors

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