Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways

  title={Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways},
  author={Yehoshua Enuka and Israel Hanukoglu and Oded Edelheit and Hananya Vaknine and A. Hanukoglu},
  journal={Histochemistry and Cell Biology},
  • Yehoshua Enuka, Israel Hanukoglu, +2 authors A. Hanukoglu
  • Published 2011
  • Medicine, Biology
  • Histochemistry and Cell Biology
  • Epithelial sodium channels (ENaCs) are located on the apical surface of cells and funnel Na+ ions from the lumen into the cell. ENaC function also regulates extracellular fluid volume as water flows across membranes accompanying Na+ ions to maintain osmolarity. To examine the sites of expression and intracellular localization of ENaC, we generated polyclonal antibodies against the extracellular domain of human α-ENaC subunit that we expressed in E. coli. Three-dimensional (3D) confocal… CONTINUE READING
    ENaCs and ASICs as therapeutic targets.
    • 55
    • PDF
    Ion channels in the endometrium: regulation of endometrial receptivity and embryo implantation.
    • 60
    • Highly Influenced
    • PDF
    Progress in ciliary ion channel physiology
    • 24
    • PDF
    The chondrocyte primary cilium.
    • 28
    • PDF


    Publications referenced by this paper.
    Overview of structure and function of mammalian cilia.
    • 779
    • PDF
    Motile Cilia of Human Airway Epithelia Are Chemosensory
    • 494
    • Highly Influential
    • PDF
    Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels.
    • 8,217
    • PDF
    Ciliogenesis: building the cell's antenna
    • 685
    • PDF
    Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.
    • 288
    Aldosterone-mediated regulation of ENaC alpha, beta, and gamma subunit proteins in rat kidney.
    • 293
    • Highly Influential
    Pulmonary epithelial sodium-channel dysfunction and excess airway liquid in pseudohypoaldosteronism.
    • 246