Epithelial sodium channel related to proteins involved in neurodegeneration

  title={Epithelial sodium channel related to proteins involved in neurodegeneration},
  author={Cecilia M. Canessa and J. D. Horisberger and Bernard C Rossier},
THE epithelial amiloride-sensitive sodium channel constitutes the rate limiting step for sodium reabsorbtion by the epithelia lining the distal part of the kidney tubule, the urinary bladder and the distal colon. Reabsorbtion of sodium through this channel, which is regulated by hormones such as aldosterone and vasopressin, is one of the essential mechanisms involved in the regulation of sodium balance, blood volume and blood pressure1–6. Here we isolate a DNA from epithelial cells of rat… CONTINUE READING
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