Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.

@article{Chantret1988EpithelialPV,
  title={Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines.},
  author={Isabelle Chantret and Alain Barbat and Elisabeth Dussaulx and Michael G. Brattain and Alain Zweibaum},
  journal={Cancer research},
  year={1988},
  volume={48 7},
  pages={1936-42}
}
Twenty human colon carcinoma cell lines were studied for their ability to develop some of the characteristics of the normal intestinal epithelium, e.g., epithelial polarity, presence of the actin-binding protein villin, or the occurrence of an enterocytic differentiation either when cultured under standard conditions, as for Caco-2 cells, or when grown in a glucose-free medium, as for HT-29 cells. Except for the regular presence of villin, which can be considered a marker of the colonic origin… CONTINUE READING
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