Epithelial morphogenesis in embryos: asymmetries, motors and brakes.

  title={Epithelial morphogenesis in embryos: asymmetries, motors and brakes.},
  author={Sophie Quintin and Christelle Gally and Michel Labouesse},
  journal={Trends in genetics : TIG},
  volume={24 5},
Epithelial cells play a central role in many embryonic morphogenetic processes, during which they undergo highly coordinated cell shape changes. Here, we review some common principles that have recently emerged through genetic and cellular analyses performed mainly with invertebrate genetic models, focusing on morphogenetic processes involving epithelial sheets. All available data argue that myosin II is the main motor that induces cell shape changes during morphogenesis. We discuss the control… CONTINUE READING

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