Epithelial-mesenchymal transitions: insights from development.

@article{Lim2012EpithelialmesenchymalTI,
  title={Epithelial-mesenchymal transitions: insights from development.},
  author={Jormay Lim and Jean Paul Thiery},
  journal={Development},
  year={2012},
  volume={139 19},
  pages={
          3471-86
        }
}
Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that occurs during development and is essential for shaping embryos. Also implicated in cancer, this morphological transition is executed through multiple mechanisms in different contexts, and studies suggest that the molecular programs governing EMT, albeit still enigmatic, are embedded within developmental programs that regulate specification and differentiation. As we review here, knowledge garnered from… CONTINUE READING

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