Epithelial maturation and molecular biology of oral HPV

  title={Epithelial maturation and molecular biology of oral HPV},
  author={Liviu Feller and Razia RAG Khammissa and Neil Hamilton Wood and Johan J Lemmer},
  booktitle={Infectious Agents and Cancer},
Human papillomavirus (HPV) is widespread and can cause latent infection in basal cells, with low HPV DNA copy-number insufficient for transmission of infection; can cause subclinical infection that is active but without clinical signs; or can cause clinical infection leading to benign, potentially malignant or malignant lesions. The HPV cycle is influenced by the stage of maturation of the infected keratinocytes, and the production of virions is restricted to the post-mitotic suprabasal… CONTINUE READING
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