Epithelial expression of SHH signaling pathway in odontogenic tumors.

@article{Zhang2006EpithelialEO,
  title={Epithelial expression of SHH signaling pathway in odontogenic tumors.},
  author={Lu Zhang and Xin-ming Chen and Zhi-Jun Sun and Zhuan Bian and Ming-Wen Fan and Zhi Chen},
  journal={Oral oncology},
  year={2006},
  volume={42 4},
  pages={
          398-408
        }
}
Sonic hedgehog (SHH) signaling pathway plays a critical role in tooth development. Recent studies indicate that SHH signaling pathway activation occurs both in the odontogenic cyst and ameloblastoma. However, the association of SHH pathway with other subtypes of odontogenic tumor is not well documented. The objective of this paper is to investigate the protein distribution of SHH and its receptor PTC, SMO and transcription factor GLI1 in various odontogenic tumors. Odontogenic tumor tissues… CONTINUE READING
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