Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry.

@article{Eckmann1993EpithelialCS,
  title={Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry.},
  author={Lars Eckmann and Martin F. Kagnoff and Joshua Fierer},
  journal={Infection and immunity},
  year={1993},
  volume={61 11},
  pages={4569-74}
}
Bacterial invasion of mucosal surfaces results in a rapid influx of polymorphonuclear leukocytes. The chemotactic stimulus responsible for this response is not known. Since epithelial cells are among the first cells entered by many enteric pathogens, we investigated the ability of epithelial cells to provide an early signal for the mucosal inflammatory response through the release of chemotactic cytokines. As shown herein, the chemokine interleukin-8 (IL-8), a potent chemoattractant and… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 222 extracted citations

Similar Papers

Loading similar papers…