Epithelial cell shape: cadherins and small GTPases.

  title={Epithelial cell shape: cadherins and small GTPases.},
  author={Vania M. M. Braga},
  journal={Experimental cell research},
  volume={261 1},
Cadherins are cell-cell adhesion receptors that are essential for the establishment of the epithelial cell shape and maintenance of the differentiated epithelial phenotype. In order to show efficient adhesion, cadherin receptors require an association with actin filaments and the activity of RHO proteins. The RHO family of small GTPases is primarily involved in the reorganization of the cytoskeleton. In different cell types, each member of the family can induce specific types of organization of… CONTINUE READING

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