Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression.

@article{Hudson2001EpithelialCD,
  title={Epithelial cell differentiation pathways in the human prostate: identification of intermediate phenotypes by keratin expression.},
  author={David Hudson and Adam T Guy and Patrick Fry and M J O'hare and Fiona M Watt and John R. W. Masters},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2001},
  volume={49 2},
  pages={271-8}
}
The prostate grows slowly throughout adult life, leading to benign prostatic hyperplasia (BPH), which often results in urethral obstruction in later years. The symptoms of BPH are the second most common reason for surgery in men over 65. The aim of this study was to determine the relationship between cell proliferation and cell differentiation in BPH tissue. Using multiple antibodies, simultaneously detected with different fluorophore-conjugated secondary antibodies, several subpopulations of… CONTINUE READING

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Aging of the prostate epithelial stem/progenitor cell.

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View 4 Excerpts
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References

Publications referenced by this paper.
Showing 1-10 of 27 references

Cell-cell interaction in prostate gene regulation and cytodifferentiation.

Proceedings of the National Academy of Sciences of the United States of America • 1997
View 7 Excerpts
Highly Influenced

Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes.

The Journal of investigative dermatology • 1999
View 1 Excerpt
Highly Influenced

Antibody markers of basal cells in complex epithelia.

Journal of cell science • 1990
View 1 Excerpt
Highly Influenced

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