Epithelial barrier and ion transport in coeliac sprue: electrical measurements on intestinal aspiration biopsy specimens.

@article{Schulzke1995EpithelialBA,
  title={Epithelial barrier and ion transport in coeliac sprue: electrical measurements on intestinal aspiration biopsy specimens.},
  author={J{\"o}rg-Dieter Schulzke and Ines Schulzke and Michael Fromm and Ernst Otto Riecken},
  journal={Gut},
  year={1995},
  volume={37 6},
  pages={
          777-82
        }
}
Epithelial barrier function and ion transport was studied in coeliac sprue using a miniaturised Ussing device for measurements on diagnostic aspiration biopsy specimens from the jejunum of untreated or gluten free nourished sprue patients, or from healthy controls. Pure epithelial resistance (Re) indicating epithelial barrier function was determined by transmural alternating current impedance analysis. It was reduced by 56% in acute sprue mean (SEM) (9 (1) omega.cm2) compared with controls (20… CONTINUE READING

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