Epithelial antimicrobial peptides and proteins: their role in host defence and inflammation.

@article{Hiemstra2001EpithelialAP,
  title={Epithelial antimicrobial peptides and proteins: their role in host defence and inflammation.},
  author={Pieter S Hiemstra},
  journal={Paediatric respiratory reviews},
  year={2001},
  volume={2 4},
  pages={306-10}
}
Various antimicrobial mechanisms act in concert to protect the lung from infection by forming an efficient host defence system. Most microbial challenges are counteracted by elements of the innate immune system and antimicrobial peptides and proteins have been identified as key components of innate immunity. Although phagocytes are an important cellular source of these so-called endogenous antibiotics, it is now recognized that the airway epithelium is also a major site of synthesis… CONTINUE READING

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