Epithelial NF-κB maintains host gut microflora homeostasis

  title={Epithelial NF-κB maintains host gut microflora homeostasis},
  author={Yinon Ben-Neriah and Marc Schmidt-Supprian},
  journal={Nature Immunology},
The environment is packed with a large variety of particles, microorganisms and antigens, which are encountered by humans and animals via mucosal surfaces of the respiratory and gastrointestinal tracts. Inhaled or ingested particles can traverse these tracts and exit, or are taken up by epithelial and phagocytic cells. Either way, only a few, if any, of the particles escape unnoticed, with most being sensed by Toll-like receptors (TLRs) and nucleotidebinding oligomerization domain (Nod)–like… CONTINUE READING