Epithelial Mesenchymal Transition in Drug Resistance and Metastasis of Lung Cancer

  title={Epithelial Mesenchymal Transition in Drug Resistance and Metastasis of Lung Cancer},
  author={Fariz Nurwidya and Fumiyuki Takahashi and Akiko Murakami and Kazuhisa Takahashi},
  booktitle={Cancer research and treatment : official journal of Korean Cancer Association},
Among all types of cancer, incidence of lung cancer remains the highest with regard to cancer-related mortality. Problems contributing to recurrence of the disease include metastasis and drug resistance. Mounting evidence has demonstrated involvement of epithelial mesenchymal transition (EMT) in cancer progression. EMT is a critical mechanism ensuring tissue remodeling during morphogenesis of multicellular organisms. Therefore, understanding of the biology of this process for identification of… CONTINUE READING
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