Epistasis in Neuropsychiatric Disorders.

Abstract

The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that have… (More)
DOI: 10.1016/j.tig.2017.01.009

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