Epistasis between 5-HTTLPR and ADRA2B polymorphisms influences attentional bias for emotional information in healthy volunteers.

@article{Naudts2012EpistasisB5,
  title={Epistasis between 5-HTTLPR and ADRA2B polymorphisms influences attentional bias for emotional information in healthy volunteers.},
  author={Kris H Naudts and Ruben T Azevedo and Anthony S. David and Kees van Heeringen and Ayana A Gibbs},
  journal={The international journal of neuropsychopharmacology},
  year={2012},
  volume={15 8},
  pages={1027-36}
}
Individual differences in emotional processing are likely to contribute to vulnerability and resilience to emotional disorders such as depression and anxiety. Genetic variation is known to contribute to these differences but they remain incompletely understood. The serotonin transporter (5-HTTLPR) and α2B-adrenergic autoreceptor (ADRA2B) insertion/deletion polymorphisms impact on two separate but interacting monaminergic signalling mechanisms that have been implicated in both emotional… CONTINUE READING