Episodic ataxia results from voltage-dependent potassium channels with altered functions

Abstract

Episodic ataxia (EA) is an autosomal dominant human disorder that produces persistent myokymia and attacks of generalized ataxia. Recently, familial EA has been linked to the voltage-dependent delayed rectifier, Kv1.1, on chromosome 12. Six EA families have been identified that carry distinct Kv1.1 missense mutations; all individuals are heterozygous… (More)
DOI: 10.1016/0896-6273(95)90022-5

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@article{Adelman1995EpisodicAR, title={Episodic ataxia results from voltage-dependent potassium channels with altered functions}, author={John P Adelman and Chris Bond and Mauro Pessia and James Mayliet}, journal={Neuron}, year={1995}, volume={15}, pages={1449-1454} }