Episodic adaptive evolution of primate lysozymes

@article{Messier1997EpisodicAE,
  title={Episodic adaptive evolution of primate lysozymes},
  author={Walter Messier and C O Stewart},
  journal={Nature},
  year={1997},
  volume={385},
  pages={151-154}
}
ALTHOUGH the darwinian concept of adaptation was established nearly a century ago, it has been difficult to demonstrate rigorously that the amino-acid differences between homologous proteins from different species have adaptive significance. There are currently two major types of sequence tests for positive darwinian selection on proteins from different species: sequence convergence, and neutral rate violation (reviewed in ref. 1). Lysozymes from the stomachs of cows and langur monkeys, two… CONTINUE READING
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