Episialin acts as an antiadhesive factor in an in vitro model of human endometrial-blastocyst attachment.

@article{Chervenak2000EpisialinAA,
  title={Episialin acts as an antiadhesive factor in an in vitro model of human endometrial-blastocyst attachment.},
  author={Judith L Chervenak and Nicholas P. Illsley},
  journal={Biology of reproduction},
  year={2000},
  volume={63 1},
  pages={294-300}
}
Episialin, which is found on the apical membrane of human endometrial epithelium, has been postulated to act as an antiadhesive factor through the steric hindrance generated by its extensively glycosylated structure. The present studies were designed to test this hypothesis in an in vitro model of endometrial-blastocyst attachment. Episialin was expressed in human endometrial carcinoma cells (HEC-1A > RL95-2), and attachment of JAr choriocarcinoma cells to the endometrial cell monolayers was… CONTINUE READING

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