Epinephrine Inhibits Tumor Necrosis Factor-a and Potentiates Interleukin 10 Production during Human Endotoxemia

@inproceedings{Poll2013EpinephrineIT,
  title={Epinephrine Inhibits Tumor Necrosis Factor-a and Potentiates Interleukin 10 Production during Human Endotoxemia},
  author={Tom S. van der Poll and Susette M. Coyle and K D S M Barbosa and Carla C. Braxton and Stephen F. Lowry},
  year={2013}
}
Short-term preexposure of mononuclear cells to epinephrine inhibits LPS-induced production of TNF, whereas preexposure for 24 h results in increased TNF production. To assess the effects of epinephrine infusions of varying duration on in vivo responses to LPS, the following experiments were performed: ( a ) Blood obtained from eight subjects at 4–24 h after… CONTINUE READING