Epileptiform activity in microcultures containing one excitatory hippocampal neuron.

@article{Segal1991EpileptiformAI,
  title={Epileptiform activity in microcultures containing one excitatory hippocampal neuron.},
  author={Michael M Segal},
  journal={Journal of neurophysiology},
  year={1991},
  volume={65 4},
  pages={761-70}
}
1. Paroxysmal depolarizing shifts (PDSs) occur during interictal epileptiform activity. Sustained depolarizations are characteristic of ictal activity, and events resembling PDSs also occur during the sustained depolarizations. To study these elements of epileptiform activity in a simpler context, I used the in vitro chronic-excitatory-block model of epilepsy of Furshpan and Potter and the microculture technique of Segal and Furshpan. 2. Intracellular recordings were made from 93 single-neuron… CONTINUE READING

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