Epileptic seizures can be anticipated by non-linear analysis

@article{Martinerie1998EpilepticSC,
  title={Epileptic seizures can be anticipated by non-linear analysis},
  author={Jacques Martinerie and Claude Adam and Michel Le Van Quyen and Michel Baulac and St{\'e}phane Cl{\'e}menceau and Beatrice Renault and Francisco J. Varela},
  journal={Nature Medicine},
  year={1998},
  volume={4},
  pages={1173-1176}
}
Epileptic seizures are a principal brain dysfunction with important public health implications, as they affect 0.8% of humans. Many of these patients (20%) are resistant to treatment with drugs. The ability to anticipate the onset of seizures in such cases would permit clinical interventions. The view of chronic focal epilepsy now is that abnormally discharging neurons act as pacemakers to recruit and entrain other normal neurons by loss of inhibition and synchronization into a critical mass… CONTINUE READING
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