Epilepsy outcomes in elderly treated with topiramate.

@article{Stefan2008EpilepsyOI,
  title={Epilepsy outcomes in elderly treated with topiramate.},
  author={H. Stefan and Ludwig J. Hubbertz and Ines Peglau and Joerg Berrouschot and Burkhard Kasper and Andreas Schreiner and J. Krimmer and Barbara Schauble},
  journal={Acta neurologica Scandinavica},
  year={2008},
  volume={118 3},
  pages={
          164-74
        }
}
OBJECTIVES To explore effectiveness, tolerability and quality of life in elderly patients with epilepsy treated with topiramate. METHODS One year, open-label, flexible-dosing clinical trial. RESULTS One hundred and seven patients (mean age 69 years, 53% men) were studied during 273 +/- 141 days. The average final dose in monotherapy was 98 mg/day vs 153 mg/day in adjunctive treatment. Mean monthly cumulative seizure frequency decreased from 3.7 +/- 15 to 1.6 +/- 7.7 (n = 101, P < 0.0001… CONTINUE READING

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