Epigenomics: genome-wide study of methylation phenomena.

@article{Novik2002EpigenomicsGS,
  title={Epigenomics: genome-wide study of methylation phenomena.},
  author={Karen L. Novik and Inko Nimmrich and Buelent Genc and Sandra Maier and Christian Piepenbrock and Alexander Olek and Sebastian Beck},
  journal={Current issues in molecular biology},
  year={2002},
  volume={4 4},
  pages={
          111-28
        }
}
Epigenetics is one of the key areas of future research that can elucidate how genomes work. It combines genetics and the environment to address complex biological systems such as the plasticity of our genome. While all nucleated human cells carry the same genome, they express different genes at different times. Much of this is governed by epigenetic changes resulting in differential methylation of our genome--or different epigenomes. Individual studies over the past decades have already… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 164 REFERENCES

DNA methylation in health and disease

  • Nature Reviews Genetics
  • 2000
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Progressive de novo DNA methylation at the bcr-abl locus in the course of chronic myelogenous leukemia.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1994
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

MethyLight: a high-throughput assay to measure DNA methylation.

  • Nucleic acids research
  • 2000
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Timothy H. Bestor, Guo-liang Xu, +7 authors Evani Viegas-Péquignot
  • Nature
  • 1999
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL