Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population.

  title={Epigenome-wide inheritance of cytosine methylation variants in a recombinant inbred population.},
  author={Robert J. Schmitz and Yupeng He and Oswaldo Vald{\'e}s-L{\'o}pez and Saad M. Khan and Trupti Joshi and Mark A. Urich and Joseph R Nery and Brian W. Diers and Dong Xu and Gary Stacey and Joseph R. Ecker},
  journal={Genome research},
  volume={23 10},
Cytosine DNA methylation is one avenue for passing information through cell divisions. Here, we present epigenomic analyses of soybean recombinant inbred lines (RILs) and their parents. Identification of differentially methylated regions (DMRs) revealed that DMRs mostly cosegregated with the genotype from which they were derived, but examples of the uncoupling of genotype and epigenotype were identified. Linkage mapping of methylation states assessed from whole-genome bisulfite sequencing of 83… CONTINUE READING
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