Epigenetics of lung cancer.

  title={Epigenetics of lung cancer.},
  author={Rayleen V. Bowman and Ian Anthony Yang and Annalese B. T. Semmler and Kwun Meng Fong},
  volume={11 4},
Epigenetics is the study of heritable changes in gene expression that occur without changes in DNA sequence. It has a role in determining when and where a gene is expressed during development. Perhaps the most well known epigenetic mechanism is DNA methylation whereby cytosines at position 5 in CpG dinucleotides are methylated. Histone modification is another form of epigenetic control, which is quite complex and diverse. Histones and DNA make up the nucleosome which is the structural unit of… CONTINUE READING