Epigenetics of epithelial Na(+) channel-dependent sodium uptake and blood pressure regulation.

Abstract

The epithelial Na(+) channel (ENaC) consists of α, β, γ subunits. Its expression and function are regulated by aldosterone at multiple levels including transcription. ENaC plays a key role in Na(+) homeostasis and blood pressure. Mutations in ENaC subunit genes result in hypertension or hypotension, depending on the nature of the mutations. Transcription of… (More)
DOI: 10.5527/wjn.v4.i3.363

Topics

Cite this paper

@article{Zhang2015EpigeneticsOE, title={Epigenetics of epithelial Na(+) channel-dependent sodium uptake and blood pressure regulation.}, author={Wenzheng Zhang}, journal={World journal of nephrology}, year={2015}, volume={4 3}, pages={363-6} }