Epigenetics of colorectal cancer.

  title={Epigenetics of colorectal cancer.},
  author={Wenji Yan and Mingzhou Guo},
  journal={Methods in molecular biology},
Colorectal cancer (CRC) is one of most common malignancies and a leading cause of cancer related deaths worldwide. Epigenetic change is an important mechanism of colorectal carcinogenesis. Accumulation of epigenetic changes was found in colorectal cancer and other tumors. Aberrant changes in DNA methylation, histone modification, imprinting, and noncoding RNAs were frequently found in human colorectal cancer. Epigenetic changes may serve as a diagnostic, prognostic, and chemo-sensitive marker… CONTINUE READING
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