Epigenetics meets endocrinology.

@article{Zhang2011EpigeneticsME,
  title={Epigenetics meets endocrinology.},
  author={Xiang Zhang and Shuk-Mei Ho},
  journal={Journal of molecular endocrinology},
  year={2011},
  volume={46 1},
  pages={R11-32}
}
Although genetics determines endocrine phenotypes, it cannot fully explain the great variability and reversibility of the system in response to environmental changes. Evidence now suggests that epigenetics, i.e. heritable but reversible changes in gene function without changes in nucleotide sequence, links genetics and environment in shaping endocrine function. Epigenetic mechanisms, including DNA methylation, histone modification, and microRNA, partition the genome into active and inactive… CONTINUE READING
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