Epigenetics insights into chronic pain: DNA hypomethylation in fibromyalgia-a controlled pilot-study.

@article{Andrade2017EpigeneticsII,
  title={Epigenetics insights into chronic pain: DNA hypomethylation in fibromyalgia-a controlled pilot-study.},
  author={Daniel Ciampi de Andrade and Mariana Maschietto and Ricardo Galhardoni and Gisele Veneroni Gouveia and Thais Chile and Ana Cristina Victorino Krepischi and Camila S Dale and Andr{\'e} Russowsky Brunoni and Daniella Cardoso Parravano and Ana S Cueva Moscoso and Irina Raicher and Helena Hideko Seguchi Kaziyama and Manoel Jacobson Teixeira and Helena Paula Brentani},
  journal={Pain},
  year={2017},
  volume={158 8},
  pages={1473-1480}
}
To evaluate changes in DNA methylation profiles in patients with fibromyalgia (FM) compared to matched healthy controls (HCs). All individuals underwent full clinical and neurophysiological assessment by cortical excitability (CE) parameters measured by transcranial magnetic stimulation. DNA from the peripheral blood of patients with FM (n = 24) and HC (n… CONTINUE READING