Epigenetics in congenital diseases and pervasive developmental disorders.

@article{Kubota2008EpigeneticsIC,
  title={Epigenetics in congenital diseases and pervasive developmental disorders.},
  author={Takeo Kubota},
  journal={Environmental health and preventive medicine},
  year={2008},
  volume={13 1},
  pages={3-7}
}
Epigenetics is an intrinsic mechanism that alters gene function - not by altering DNA sequences, but by chemically modifying the DNA and chromosomal histone proteins. Epigenetics is involved in genomic imprinting and X-chromosome inactivation in humans, and the failure of this mechanism causes a subset of congenital syndromes and cancers. Until recently, it… CONTINUE READING