Epigenetics in Myeloproliferative Neoplasms

Abstract

A decade on from the description of JAK2 V617F, the MPNs are circumscribed by an increasingly intricate landscape. There is now evidence that they are likely the result of combined genetic dysregulation, with several mutated genes involved in the regulation of epigenetic mechanisms. Epigenetic changes are not due to a change in the DNA sequence but are… (More)
DOI: 10.1111/jcmm.13095

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