Epigenetics and the placenta.

  title={Epigenetics and the placenta.},
  author={Ewka C M Nelissen and Aafke P A van Montfoort and John C. M. Dumoulin and Johannes L. H. Evers},
  journal={Human reproduction update},
  volume={17 3},
BACKGROUND The placenta is of utmost importance for intrauterine fetal development and growth. Deregulation of placentation can lead to adverse outcomes for both mother and fetus, e.g. gestational trophoblastic disease (GTD), pre-eclampsia and fetal growth retardation. A significant factor in placental development and function is epigenetic regulation. METHODS This review summarizes the current knowledge in the field of epigenetics in relation to placental development and function. Relevant… CONTINUE READING