Epigenetics and the environmental regulation of the genome and its function.

@article{Zhang2010EpigeneticsAT,
  title={Epigenetics and the environmental regulation of the genome and its function.},
  author={Tie Yuan Zhang and Michael J. Meaney},
  journal={Annual review of psychology},
  year={2010},
  volume={61},
  pages={439-66, C1-3}
}
There are numerous examples in psychology and other disciplines of the enduring effects of early experience on neural function. In this article, we review the emerging evidence for epigenetics as a candidate mechanism for these effects. Epigenetics refers to functionally relevant modifications to the genome that do not involve a change in nucleotide sequence. Such modifications include chemical marks that regulate the transcription of the genome. There is now evidence that environmental events… CONTINUE READING

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References

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Showing 1-10 of 149 references

Epigenetic programming through maternal behavior

  • Icg Weaver, N Cervoni, D Alessio, Ac Champagne, Fa Seckl, Jr
  • Nature Neurosci
  • 2004
Highly Influential
11 Excerpts

Maternal effects as a model for environmentally-dependent chromatin plasticity

  • Mj Meaney, M Szyf
  • Trends Neurosci
  • 2005
Highly Influential
7 Excerpts

Anrv398-ps61-17 Ari 17

  • ANRV398-PS61-17 ARI 17
  • 2009

Differential methylation of a neuron-enriched glucocorticoid receptor gene promoter in human hippocampus is associated with early child trauma and adult psychopathology

  • Po Mcgowan, A Sasaki, S Dymov, G Turecki, M Szyf, Mj Meaney
  • Nature Neurosci
  • 2009
1 Excerpt

Downloaded from arjournals.annualreviews.org by UNIVERSITY OF ILLINOIS -CHICAGO on 12/10/09. For personal use only

  • Zhang, Meaney
  • Annu. Rev. Psychol
  • 2009

Downloaded from arjournals.annualreviews.org by UNIVERSITY OF ILLINOIS -CHICAGO on 12/10/09. For personal use only. AR398-FM ARI 7

  • Zhang, Meaney
  • Annu. Rev. Psychol
  • 2009

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