Epigenetics: principles and practice.

@article{Hamilton2011EpigeneticsPA,
  title={Epigenetics: principles and practice.},
  author={James Peter Hamilton},
  journal={Digestive diseases},
  year={2011},
  volume={29 2},
  pages={130-5}
}
Epigenetics is defined as heritable changes in gene expression that are, unlike mutations, not attributable to alterations in the sequence of DNA. The predominant epigenetic mechanisms are DNA methylation, modifications to chromatin, loss of imprinting and non-coding RNA. Epigenetic regulation of gene expression appears to have long-term effects and wide-ranging effects on health. Diet and environmental exposures may potentially alter the level and scope of epigenetic regulation, thus… CONTINUE READING
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