Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivation.

@article{Silingardi2010EpigeneticTO,
  title={Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivation.},
  author={Davide Silingardi and Manuela Scali and Giulio Belluomini and Tommaso Pizzorusso},
  journal={The European journal of neuroscience},
  year={2010},
  volume={31 12},
  pages={2185-92}
}
In mammals the development of the visual system may be altered during a sensitive period by modifying the visual input to one or both eyes. These plastic processes are reduced after the end of the sensitive period. It has been proposed that reduced levels of plasticity are at the basis of the lack of recovery from early visual deprivation observed in adult animals. A developmental downregulation of experience-dependent regulation of histone acetylation has recently been found to be involved in… CONTINUE READING

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