Epigenetic silencing of multiple genes in primary CNS lymphoma.

  title={Epigenetic silencing of multiple genes in primary CNS lymphoma.},
  author={Linda C. Chu and Charles G. Eberhart and Stuart Grossman and James G. Herman},
  journal={International journal of cancer},
  volume={119 10},
Epigenetic silencing of functionally important genes is important in the development of malignancies and is a source of potential markers for molecular detection. Primary central nervous system lymphoma (PCNSL) is an increasingly common tumor that has not been extensively examined for changes in promoter region methylation. We examined 14 tumor suppressor… CONTINUE READING