Epigenetic signatures as prognostic tools in acute myeloid leukemia and myelodysplastic syndromes.


Risk stratification in acute myeloid leukemia Acute myeloid leukemia (AML) is a heterogeneous disease with varying molecular abnormalities leading to blocked differentiation and increased proliferation of immature myeloid cells. Relapse is the leading obstacle to surviving AML, and occurs in up to 80% of the patients. The molecular heterogeneity makes… (More)
DOI: 10.2217/epi.14.32