Epigenetic regulation of reprogramming factors towards pluripotency in mouse preimplantation development.


PURPOSE OF REVIEW Pluripotency is the ability of a cell to give rise to all the tissues of the adult body. During development, both genetic and epigenetic mechanisms are proposed to be involved in the establishment of the pluripotent state in the cells of the epiblast. Here, we review recent findings on the biological function and epigenetic regulation of… (More)
DOI: 10.1097/MED.0b013e3283405325


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