Epigenetic regulation of genes in learning and memory.

@article{Roth2010EpigeneticRO,
  title={Epigenetic regulation of genes in learning and memory.},
  author={T. Roth and E. D. Roth and J. Sweatt},
  journal={Essays in biochemistry},
  year={2010},
  volume={48 1},
  pages={
          263-74
        }
}
Rapid advances in the field of epigenetics are revealing a new way to understand how we can form and store strong memories of significant events in our lives. Epigenetic modifications of chromatin, namely the post-translational modifications of nuclear proteins and covalent modification of DNA that regulate gene activity in the CNS (central nervous system), continue to be recognized for their pivotal role in synaptic plasticity and memory formation. At the same time, studies are correlating… Expand
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References

SHOWING 1-10 OF 44 REFERENCES
Regulation of chromatin structure in memory formation
  • 133
Epigenetic codes in cognition and behaviour
  • 249
  • PDF
Epigenetic dysregulation in cognitive disorders
  • 148
  • PDF
Covalent Modification of DNA Regulates Memory Formation
  • 694
Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory
  • 691
  • PDF
Epigenetic mechanisms in schizophrenia.
  • 112
DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity
  • 381
  • PDF
Recovery of learning and memory is associated with chromatin remodelling
  • 1,026
...
1
2
3
4
5
...