Epigenetic regulation of cholesterol homeostasis

  title={Epigenetic regulation of cholesterol homeostasis},
  author={Steve Meaney},
  booktitle={Front. Genet.},
Although best known as a risk factor for cardiovascular disease, cholesterol is a vital component of all mammalian cells. In addition to key structural roles, cholesterol is a vital biochemical precursor for numerous biologically important compounds including oxysterols and bile acids, as well as acting as an activator of critical morphogenic systems (e.g., the Hedgehog system). A variety of sophisticated regulatory mechanisms interact to coordinate the overall level of cholesterol in cells… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 6 times over the past 90 days. VIEW TWEETS


Publications referenced by this paper.
Showing 1-10 of 104 references

Post - transcriptional control of the LDLR pathway by cholesterol - responsive microRNAs

  • A. Salerno, K. Rayner, A. Wanschel, S. Oldebeken, E. Scotti, P. Tontonoz
  • Athersc . Thromb . Vasc . Biol .
  • 2013
Highly Influential
4 Excerpts

Histone deacetylase

  • N. Sangster-Guity, P. J. McCormick
  • 2008
Highly Influential
13 Excerpts

Epigenetic regulation of cholesterol homeostasis

  • S Citation Meaney
  • Copyright © 2014 Meaney
  • 2014

Similar Papers

Loading similar papers…