Epigenetic regulation and role of LINE-1 retrotransposon in embryogenesis

Abstract

LINE-1 retrotransposon is the most common mobile genetic element in the genomes of various mammals, including humans. Its genes are represented by the greatest number of copies. For a long time, it has been considered that the presence of LINE-1 in genome reflects the limited ability of cells to eliminate it, and the retrotransposon activity is negative… (More)
DOI: 10.1134/S1022795416120152

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