Epigenetic pathways and glioblastoma treatment

@inproceedings{Clarke2013EpigeneticPA,
  title={Epigenetic pathways and glioblastoma treatment},
  author={Jennifer Clarke and Clara Penas and Chiara Pastori and Ricardo J. Komotar and Amade Bregy and Ashish Harish Shah and Claes Wahlestedt and Nagi George Ayad},
  booktitle={Epigenetics},
  year={2013}
}
Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Standard GBM treatment includes maximal safe surgical resection with combination radiotherapy and adjuvant temozolomide (TMZ) chemotherapy. Alarmingly, patient survival at five-years is below 10%. This is in part due to the invasive behavior of the tumor and the resulting inability to resect greater than 98% of some tumors. In fact, recurrence after such treatment may be inevitable, even in cases where gross total… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
18 Citations
70 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 70 references

Oncogenic effects of miR10 b in glioblastoma stem cells

  • F Guessous, M Alvarado-Velez, L Marcinkiewicz, Y Zhang, J Kim, S Heister
  • J Neurooncol
  • 2013

Similar Papers

Loading similar papers…