Epigenetic modifications of the neuroproteome.

@article{Brunner2012EpigeneticMO,
  title={Epigenetic modifications of the neuroproteome.},
  author={Andrea M. Brunner and Ry Yves Tweedie-Cullen and Isabelle M Mansuy},
  journal={Proteomics},
  year={2012},
  volume={12 15-16},
  pages={2404-20}
}
In the central nervous system, epigenetic processes are involved in a multitude of brain functions ranging from the development and differentiation of the nervous system through to higher-order cognitive processes such as learning and memory. This review summarises the current state of the art for the proteomic analysis of the epigenetic regulation of gene expression, in particular the PTM of histones, in the brain and cellular model systems. It describes the MS technologies that have helped… CONTINUE READING

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