Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.

Abstract

BACKGROUND The mechanisms of estrogen insensitivity or estrogen resistance in ovarian cancer cells are not known. Studies on regulation of the estrogen receptor (ER) gene have suggested a role for epigenetics in silencing ER expression. MATERIALS AND METHODS Cells from insensitive ovarian cancer cells, SKOV3 and HEY, were cultured with and without the DNA… (More)

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@article{Yap2009EpigeneticMO, title={Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.}, author={Oi Wah Stephanie Yap and G. Jayarama Bhat and Liang Liu and Trygve O. Tollefsbol}, journal={Anticancer research}, year={2009}, volume={29 1}, pages={139-44} }