Epigenetic mechanisms in the pathogenesis of diabetic foot ulcers.

  title={Epigenetic mechanisms in the pathogenesis of diabetic foot ulcers.},
  author={Haloom Rafehi and Assam El-Osta and Tom C. Karagiannis},
  journal={Journal of diabetes and its complications},
  volume={26 6},
The incidence of diabetes mellitus, a chronic metabolic disease associated with both predisposing genetic and environmental factors, is increasing globally. As a result, it is expected that there will also be an increasing incidence of diabetic complications which arise as a result of poor glycemic control. Complications include cardiovascular diseases, nephropathy, retinopathy and diabetic foot ulcers. The findings of several major clinical trials have identified that diabetic complications… CONTINUE READING


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